IMMUNOLOGIC STATUS AND IMMUNOLOGIC CHANGES BY TREATMENT IN BREAST CANCER PATIENTS
نویسندگان
چکیده
منابع مشابه
Immunologic approaches to breast cancer treatment.
The need for less toxic adjuvant therapies and a better understanding of the processes by which the immune system can eradicate micrometastatic disease has generated significant interest in breast cancer immunotherapy. There are many potential approaches to stimulating an immune response against a tumor, each with relative advantages and disadvantages in regards to cost, immunogenicity, and cli...
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Breast cancer is an immunogenic tumor. Over the last decade, investigations have shown that patients with breast cancer have pre-existent immune responses, both humoral and cellular, against a variety of proteins expressed in their tumors. Researchers using genomic and proteomic techniques have defined dozens of proteins that may serve as immunologic targets in breast cancer patients. In additi...
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The forkhead transcription factor FOXP3 is necessary for induction of regulatory T lymphocytes (Tregs) and their immunosuppressive function. We have previously demonstrated that targeting Tregs by vaccination of mice with murine FOXP3 mRNA-transfected dendritic cells (DCs) elicits FOXP3-specific T cell responses and enhances tumor immunity. It is clear that FOXP3 expression is not restricted to...
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UNLABELLED Several studies have shown a heightened inflammatory state in frail older adults, marked by high serum levels of interleukin-6 and C-reactive protein and an increased number of circulating leukocytes. Activation of monocytes and macrophages, marked by increased levels of neopterin, may contribute to chronic inflammation in the frail older adult. However, the reduced mononuclear cell ...
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Background Acute mental stress evokes responses in the cardiovascular and the immune systems. In particular, the subset of natural killer (NK) cells is found to be responsive to mental stress. The role of ,B-adrenergic mechanisms in these processes is the subject of this investigation. Methods and Results Healthy male volunteers (n=31) were subjected to two consecutive mental tasks. Subjects we...
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ژورنال
عنوان ژورنال: The KITAKANTO Medical Journal
سال: 1984
ISSN: 0023-1908,1883-6135
DOI: 10.2974/kmj1951.34.193